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Workshop "Bayesian methods in the development and assessment of new therapies"

Workshop of the IBS-DR working group Bayes Methods.
Göttingen, December 6-7, 2018


    Niedersächsische Staats- und Universitätsbibliothek (SUB)
    Großer Seminarraum (1st floor)
    Platz der Göttinger Sieben 1
    51°32'23.2"N  9°56'07.8"E


Announcement and call for papers


Program (PDF)


Thursday, December 6, 2018:

09:00-10:30Tutorial: Sebastian Weber, Heinz Schmidli (Novartis AG, Basel): Use of historical data: Methods, applications and implementation with the R package RBesT[slides 1]
[slides 2]
[course material]
10:30-11:00Coffee break
11:00-12:00Tutorial continued
12:00-13:00Lunch break
13:00-14:00Heinz Schmidli (Novartis AG, Basel): Bayesian applications in drug development[abstract] [slides]
14:00-14:20Ralf Bender (IQWiG, Köln): Applications of Bayesian methods in health technology assessment[abstract] [slides]
14:20-14:50Coffee break
14:50-15:30Sibylle Sturtz (IQWiG, Köln): Meta-analysis using Bayesian methods: Applications in systematic reviews[abstract] [slides]
15:30-15:40Norbert Benda (BfArM, Bonn): Introduction to panel discussion[slides]
15:40-16:10Panel discussion
16:10-16:40Coffee break
16:40-17:10Christian Röver (UMG, Göttingen): Model averaging for robust extrapolation in evidence synthesis[abstract] [slides]
17:10-17:40Manuel Wiesenfarth (DKFZ, Heidelberg): Quantification of prior impact in terms of prior effective historical and current sample size[abstract] [slides]


Friday, December 7, 2018:

08:30-10:00Thomas Jaki (Lancaster University): Multi-objective dose-finding[abstract] [slides]
10:00-10:30Coffee break
10:30-11:00Burak K. Günhan (UMG Göttingen): Phase I dose-escalation trials with more than one dosing regimen[abstract] [slides]
11:00-11:30Stefan Klein (Bayer AG, Berlin): Bayesian concept for combined phase 2a/b trials[abstract] [slides]
11:30-12:00Frank Fleischer (Boehringer Ingelheim, Biberach): Bayesian MCPMod[abstract] [slides]
12:00-13:00Lunch break
13:00-13:30Working group business meeting
13:30-14:00Eleni Vradi (Bayer AG, Berlin): Bayesian variable selection and classification with control of predictive values[abstract] [slides]
14:00-14:30Arne Ring (Medac, Wedel): Planning crossover bioequivalence trials: Systematic review and application of assurance[abstract]
14:30-15:00Coffee break
15:00-15:30Annette Kopp-Schneider (DKFZ, Heidelberg): Bayesian dynamic borrowing of external information: What can be gained in terms of frequentist power?[abstract] [slides]
15:30-16:00Arne Ring (Medac, Wedel): Scientific collaboration with African students in mathematics, exemplified for a project to determine the assurance during project planning of clinical development programs[abstract] [slides]