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Adaptive Designs and Multiple Testing Procedures

Joint Working Group (Section) of the ROeS and the German Region of the IBS

The working group has the aim to promote the development and application of biostatistical procedures in the fields of multiple testing and group adaptive designs. The working group organises an annual workshop which offers presentations on the state of the art research on adaptive designs and multiple testing procedures and related fields, but also showcases of the practical implementation of these methods.


If you want to keep up-to-date with the activities of the working group, please contact the working group chair in order to subscribe to our mailing list. You may update your contact details or unsubscribe from the mailing list at any time by informal email notification to the working group chair. Contact details are given below.


Next workshop:

The Workshop ADMTP 2022 will take place in Heidelberg on June 29th to July 1st. Further details on format and registration will follow shortly!

Past workshops:

2021 Göttingen (Online):

Abstract booklet

2020 Online-Meeting:


2019 Münster:

Abstract booklet

2018 Bremen:

Workshop website

2017 Cambridge, UK:

Workshop website

2016 Padua:

Program & Presentatinos

2015 Köln:

Program & Presentations

2014 Basel:

Abstract booklet
Workshop website

2012 Heidelberg:

Abstract booklet
Workshop website (offline)

2011 Lancaster:

2010 Vienna:

2009 Warwick:

2008 Mainz:

2007 Vienna:

The workshop of the working group was merged into the larger MCP meeting:



Related events and activities of the working group:


Adaptive designs for clinical trials in the context of the COVID-19 pandemic

The working group organized the formation of expert panels to elaborate of the challenges and opportunities of adaptive designs for clinical trials in the pandemic setting. Two papers originated from these activities: (i) a paper on Efficient adaptive designs for clinical trials of interventions for COVID-19, (ii) a paper Clinical trials impacted by the COVID-19 pandemic: Adaptive designs to the rescue?


FDA guidance on "Adaptive Designs for Clinical Trials of Drugs and Biologics"

Members of the working group have submitted comments on the recent draft of this guidance. 


New Perspectives in Multiple Testing - 80 years after Bonferroni, 9.10.2015


MCP Conference, Hyderabad, India, September 2, 2015 to September 5, 2015


MCP Conference, Southampton, UK, 8.-11. July 2013


ROeS Meeting 2013, Dornbirn, AT

Session "Flexible and Adaptive Designs"


ISCI Conference 2013, Hannover

Session: recent approaches in simultaneous inference (multiple testing), their bio-medical applications and related software


ISBS Symposium 2011, Berlin

The working group organized a double session at the Symposium in Berlin ( on the topic of this draft FDA guidance.


CEN 2011, Zurich

The working group organized a session on adaptive enrichment designs (


FDA guidance on "Adaptive Design Clinical Trials forDrugs and Biologics"

Members of the working group have submitted comments on the recent draft of this guidances (available at A corresponding position paper was published in a special issue of the Journal of Biopharmaceutical Statistics (issue 6, 2010, p. 1125-1131).

Dr. Lisa V Hampson
Statistical Methodology and Consulting, Novartis Pharma
E-Mail: lisa.hampson(at)


Dr. Thomas Asendorf
Department of Medical Statistics, Clinical Trial Unit UMG
University of Göttingen
von Siebold Str. 3
37075 Göttingen, Germany
Tel.: +49 551-39-63026
Fax: +49 551-39-4995
E-Mail: Thomas.Asendorf(at)


Bylaws (Satzung) of the working group - in German.