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Adaptive Designs and Multiple Testing Procedures

Joint Working Group (Section) of the ROeS and the German Region of the IBS

The working group has the aim to promote the development and application of biostatistical procedures in the fields of multiple testing and group adaptive designs. The working group organises an annual workshop which offers presentations on the state of the art research on adaptive designs and multiple testing procedures and related fields, but also showcases of the practical implementation of these methods. practical implementation of these methods.

Next workshop:

The next workshop on Adaptive Designs and Mulitple Testing Procedures will be held in Spring, or early Summer 2018 at the University of Bremen, Germany.


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Recent activities of the working group:

Past workshops:

2017 Cambridge, UK

Workshop website

2016 Padua:

Program & Presentatinos

2015 Köln:

Program & Presentations

2014 Basel:

Abstract booklet
Workshop website

2012 Heidelberg:

Abstract booklet
Workshop website (offline)

2011 Lancaster:

2010 Vienna:

2009 Warwick:

2008 Mainz:

2007 Vienna:

The workshop of the working group was merged into the larger MCP meeting:

Related events and activities of the working group:

New Perspectives in Multiple Testing - 80 years after Bonferroni, 9.10.2015

MCP Conference, Hyderabad, India, September 2, 2015 to September 5, 2015

MCP Conference, Southampton, UK, 8.-11. July 2013

ROeS Meeting 2013, Dornbirn, AT

Session "Flexible and Adaptive Designs"

ISCI Conference 2013, Hannover

Session: recent approaches in simultaneous inference (multiple testing), their bio-medical applications and related software

ISBS Symposium 2011, Berlin

The working group organized a double session at the Symposium in Berlin ( on the topic of this draft FDA guidance.

CEN 2011, Zurich

The working group organized a session on adaptive enrichment designs (

FDA guidance on "Adaptive Design Clinical Trials forDrugs and Biologics"

Members of the working group have submitted comments on the recent draft of this guidances (available at A corresponding position paper was published in a special issue of the Journal of Biopharmaceutical Statistics (issue 6, 2010, p. 1125-1131).

DI Dr. Florian Klinglmueller
Department Biologicals, Preclinical & Statistical Assessment
Austrian Medicines & Medical Devices Agency
AGES - Austrian Agency for Health and Food Safety
Traisengasse 5 | 1200 Vienna
Tel.: +43 (0)5 0555-36624
E-Mail: florian.klinglmueller(at)


Dr. rer. nat. Rene Schmid, Dipl.-Math.
Westfälische Wilhelms-Universität Münster
Institute of Biostatistics and Clinical Research
Schmeddingstraße 56
48149 Münster
Tel.: +49 251 83 58370
Fax: +49 251 83 5 52 77

Bylaws (Satzung) of the working group - in German.